Preheat the oven to 350°F. Spray a sheet pan with cooking spray or line it with foil and set aside.
In a small bowl, whisk together the olive oil, honey, garlic, hot sauce, water, and salt/pepper to taste. Set aside.
Arrange the pork loin and vegetables onto the prepared sheet pan. Pour the sauce over everything, and sprinkle with garlic powder, paprika, salt, and pepper to taste. Toss to coat evenly.
Bake for 25-30 minutes or until the vegetables are tender and the pork reaches a minimum internal temperature of 145°F.